Journal: Frontiers in Genetics
Article Title: The impact of decreased expression of SVEP1 on abnormal neovascularization and poor prognosis in patients with intrahepatic cholangiocarcinoma
doi: 10.3389/fgene.2022.1127753
Figure Lengend Snippet: SVEP1 expression is positively related to the expression of Ang-1, which plays an important role in the maintenance of vascular stability. (A) Representative IHC images of Ang-1 in ICC tissues. (B) IHC image quantification results. Relative proportions of high and low levels of Ang-1 in the group of tumor tissues with high and low expression of SVEP1, and the correlation analysis between Ang-1 and SVEP1. (C–D) Correlation of Ang-1 expression with the OS (C) and DFS (D) time of ICC patients, respectively.
Article Snippet: The primary antibody included rabbit anti-SVEP1 polyclonal antibody (Abcam, cat#ab121677), rabbit anti-Angiopoietin-1 (Ang-1) polyclonal antibody (Bioss, cat#bs-0800R), and mouse anti-Ki-67 monoclonal antibody (Zhongshan Goldbridge Biotechno-logy CO., Ltd., Beijing, China).
Techniques: Expressing